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How Exercise Affects Female Hormones

Written by Jamie Braithwaite

November 25, 2025

Reviewed by:

Dr Thom Phillips
Happy woman resting after workout stock photo
In this article:

We all know that exercise is a cornerstone of good health. It builds muscle, strengthens our heart, and clears our minds. But its relationship with our hormones is far more complex, especially for women. This relationship is a delicate balancing act. The right amount and type of exercise can be powerfully regulating, but too much can cause disruption.

Your hormones are managed by the endocrine system, the body’s intricate messenger service. This system controls everything from your mood and metabolism to your menstrual cycle. Exercise is one of the most powerful inputs that can influence these hormonal signals.

So, how does exercise affect female hormones? Does it help or hinder? The answer is: it does both.

This blog explores the link between exercise and your key female hormones. We’ll cover which hormones are released when you work out, how exercise impacts oestrogen and progesterone, and what happens when you overdo it. We will also explain how you can stop guessing and start measuring your hormone levels with a female hormone test.

Hormones Released During Exercise

The most immediate effect of exercise is the release of “happy hormones.” This is your body’s short-term response to the physical stress of a workout.

  • Endorphins

    These are the body's natural painkillers. They are released by the brain during strenuous exercise, creating the famed "runner's high." This effect can reduce feelings of pain and produce a sense of euphoria[1].

  • Dopamine

    Dopamine is a neurotransmitter that’s crucial for your brain's reward system. When you set and achieve a fitness goal (like running a 5k or lifting a new personal best), your brain releases dopamine, which makes you feel accomplished and motivates you to do it again.

  • Serotonin

    This hormone is key for regulating mood, sleep, and appetite. Exercise is known to boost serotonin production, which is why regular physical activity is one of the most effective non-medical strategies for managing symptoms of anxiety and depression [2].

  • Adrenaline and Noradrenaline

    These are your fight or flight hormones. They surge at the start of a workout, increasing your heart rate, pumping more blood to your muscles, and telling your body to release stored glucose for energy. This is what gives you that immediate "get up and go" feeling.

Exercise and Female Hormones

Beyond the immediate feel-good effect, exercise has a profound, long-term impact on your main sex hormones. This is where balance becomes critical.

Oestrogen

Oestrogens (specifically Oestradiol) are your primary female sex hormones. They regulate your menstrual cycle, maintain bone density, and affect your mood.

The link between exercise and oestrogen is positive. Regular, moderate exercise can help regulate oestrogen levels. It is particularly beneficial for women with high oestrogen (oestrogen dominance), as it can help the body metabolise and excrete excess hormones. Studies have shown that consistent physical activity is linked to a lower lifetime risk of oestrogen-related conditions [3].

However, the balance is delicate. Very high-intensity or excessive exercise, without adequate rest and nutrition, can have the opposite effect. It can lead to suppressed oestrogen production, contributing to irregular periods or even amenorrhoea (the absence of a period).

Progesterone

Progesterone is the balancing partner to oestrogen. It is produced after ovulation in the second half of your menstrual cycle (the luteal phase).

This hormone is particularly sensitive to the stress signals created by exercise. If your body perceives that it is under too much stress (from overtraining, under-eating, or both), it may suppress ovulation to conserve energy. No ovulation means no progesterone is produced, leading to an imbalance with oestrogen. This can result in symptoms like PMS, heavy periods, and anxiety [4].

Testosterone

When women hear testosterone, they often think of it as a male-only hormone. In reality, it is vital for female health, playing a key role in muscle mass, bone density, energy levels, and libido.

Exercise, particularly resistance (strength) training, is fantastic for maintaining healthy testosterone levels in women. As you build lean muscle, your body gets a small, healthy boost of testosterone. This acute hormonal response is essential for repairing and building new muscle tissue after your workout [5].

"Regular exercise profoundly influences hormonal equilibrium throughout the body. Physical activity reduces cortisol levels, mitigating chronic stress while boosting endorphins that enhance mood and pain tolerance. Exercise increases insulin sensitivity, helping regulate blood sugar and reducing diabetes risk. It stimulates growth hormone and testosterone production, supporting muscle maintenance and metabolic health in both sexes. For women, consistent movement helps balance oestrogen and progesterone, potentially easing menstrual irregularities and menopausal symptoms. Even moderate activity—like brisk walking—triggers these beneficial hormonal responses. The cumulative effect is improved sleep, stable energy, better weight management, and enhanced well-being."

Overtraining and Hormonal Imbalance

Your body doesn’t know the difference between running from a threat, a stressful day at work, or a 90-minute high-intensity spin class. It just registers stress. And its main stress hormone is cortisol.

A short-term rise in cortisol during exercise is normal and beneficial as it helps you mobilise energy. The problem begins when cortisol is chronically high. This happens when you are:

  • Exercising too intensely, too often

  • Not getting enough sleep

  • Not eating enough calories to fuel your activity

  • Experiencing high levels of mental or emotional stress

This state of chronic stress is often called Relative Energy Deficiency in Sport (RED-S), or Overtraining Syndrome.

When your body is in this survival mode, it begins to shut down non-essential functions to conserve energy. For women, the first system to be deprioritised is often the reproductive system. Your brain stops sending the right signals to your ovaries, leading to:

  • Low Oestrogen

    Resulting in missed periods (amenorrhoea) and poor bone health.

  • Low Progesterone

    Caused by a lack of ovulation.

  • High Cortisol

    Which can cause fatigue, a weakened immune system, and stubborn belly fat.

Symptoms that you might be overtraining and disrupting your hormones include:

  • Persistent fatigue and low energy

  • Irregular or missing periods

  • Difficulty sleeping

  • Getting sick more often

  • Nagging injuries or sore muscles that don't heal

  • A decline in your athletic performance

"RED-s occurs when an individual does not consume enough calories to support their exercise demands, creating a dangerous energy deficit. This syndrome disrupts multiple bodily systems, particularly hormonal function. In women, RED-S can halt menstruation, decrease bone density, and increase fracture risk dramatically. Men experience lowered testosterone, reduced libido, and compromised bone health too. Both sexes face weakened immune function, impaired recovery, cardiovascular issues, and declining performance—the opposite of athletic goals. RED-s also affects mental health, causing irritability, depression, and disordered eating patterns. It’s also important to remember that RED-s is not limited to high level professional athletes, anyone is susceptible if they’re not eating enough!"

Exercise for Different Female Life Stages

Your hormonal landscape changes throughout your life, and your exercise routine should adapt with it.

During Your Menstrual Cycle

Your hormones aren’t the same every day of the month. Tailoring your workouts to your cycle can be a game-changer.

  • Follicular Phase (Day 1 to Ovulation)

    Oestrogen is rising, and your energy is high. This is a great time for high-intensity workouts, strength training, and pushing for new personal bests.

  • Luteal Phase (Ovulation to Period)

    Progesterone rises, and you may feel warmer and more tired. Your body may also be more reliant on fat for fuel. This is an ideal time for steady-state cardio (like jogging or cycling), yoga, and lighter-bodyweight workouts.

  • Menstruation

    Energy is typically at its lowest. Restorative activities like walking, stretching, and gentle yoga are perfect. Listen to your body and rest if you need to.

Our MyFORM™ female hormone mapping test can help you map your unique hormonal fluctuations across your entire cycle, giving you the power to train with your biology, not against it.

During Perimenopause and Menopause

As you enter perimenopause, your oestrogen and progesterone levels begin to fluctuate and eventually decline. Exercise becomes one of the most powerful tools for managing this transition.

  • It protects your bones

    The decline in oestrogen accelerates bone density loss. Strength training and impact-bearing exercises (like running or jumping) are critical for maintaining bone strength and reducing the risk of osteoporosis[6].

  • It manages symptoms

    Regular exercise has been shown to reduce the severity of common perimenopause symptoms like hot flushes, night sweats, and mood swings.

  • It preserves muscle

    We naturally lose muscle mass as we age (sarcopenia). Resistance training is the single best way to combat this, keeping your metabolism high and your body strong.

A Perimenopause Blood Test can help you understand where you are in this transition so you can make informed choices about your health and fitness.

How Blood Testing Can Help You Find Your Balance

So, how do you know if your exercise routine is helping or harming your hormones? You test, you don’t guess.

You can’t feel your exact oestrogen level, and symptoms like fatigue or mood swings can have many different causes. This is where blood testing provides clarity.

A comprehensive female hormone blood test provides a precise snapshot of your hormonal health. You can measure your:

  • Oestradiol and Progesterone: To see if they are balanced and within the optimal range for your cycle phase.
  • Testosterone: To ensure you have healthy levels for energy and muscle.
  • LH and FSH: Key brain-signalling hormones that control your cycle.
  • Cortisol: To check if your stress levels are putting you at risk of overtraining.

By getting a baseline, you can see where you stand. If you’re feeling great, the test can confirm your routine is working. If you’re struggling with symptoms, the results can pinpoint a specific imbalance, giving you and your doctor a clear path forward. You might discover you need more rest, more fuel, or perhaps a different style of training.

Frequently Asked Questions

Can exercise cause or worsen hormonal acne?

It’s complicated. For most people, exercise helps acne by reducing stress (and therefore cortisol) and improving blood flow. However, sweat, friction from clothing, and the post-workout hormonal surge can, for some people, be a temporary trigger. The solution is usually not to stop exercising, but to cleanse your face immediately after your workout and ensure you’re not overtraining, which can disrupt your androgen levels.

Does exercise increase human growth hormone (HGH)?

Yes. Human Growth Hormone (HGH) is vital for cell repair, metabolism, and building muscle. Your body releases HGH in pulses, primarily during deep sleep. However, high-intensity exercise (both strength training and interval sprints) is a potent stimulus for HGH release[7]. This is one of the key mechanisms by which exercise helps build muscle and burn fat.

Is long-distance running bad for female hormones?

It can be, but it isn’t inherently bad. The danger for many female long-distance runners is failing to consume enough calories to match their high energy expenditure. This energy deficit is what triggers the body’s stress response, leading to high cortisol, low oestrogen, and the loss of the menstrual cycle (part of the RED-S condition)[4]. If a runner fuels properly, prioritises rest, and incorporates strength training, running can be perfectly compatible with healthy hormones.

What are the short-term effects of exercise on the endocrine system?

In the short term, the endocrine system goes on high alert. The adrenal glands release adrenaline and cortisol to mobilise energy (glucose) from your liver and fat stores. The brain releases endorphins to manage pain. Your pancreas also adjusts insulin secretion to ensure your working muscles can access the fuel they need. This acute response is a healthy, adaptive stress.

Can exercise cause spotting between periods?

Yes, this is possible for a few reasons. High-impact exercise like running can sometimes cause spotting due to the physical jarring. In other cases, spotting can be a sign of a new exercise programme placing stress on the body, leading to a temporary hormonal fluctuation. However, if spotting is new, persistent, or accompanied by other symptoms, it’s essential to stop and speak with your doctor, as it can also be a sign of an underlying issue like a low progesterone-to-oestrogen ratio, fibroids, or polyps.

Article references

  1. E. E. Hill et al., "Exercise and circulating cortisol levels: the intensity threshold effect," J Endocrinol Invest, vol. 31, no. 7, pp. 587–591, Jul. 2008.

  2. J. S. B. Martins et al., "Effects of Exercise on Anxiety, Depression, and Mood," in Physical Activity and the Brain, J. B. E. G. B. V. A. F. Rocha, Ed. New York, NY: Springer, 2018, pp. 201–211.

  3. C. M. Friedenreich, H. K. Neilson, and M. E. C. McNeely, "Updated review of exercise and breast cancer risk," Compr Physiol, vol. 5, no. 3, pp. 1433–1463, Jun. 2015.

  4. M. J. De Souza et al., "High prevalence of low body mass index and menstrual disturbances in elite skateboarders," Br J Sports Med, vol. 44, no. 1, pp. 19–25, Jan. 2010.

  5. W. J. Kraemer and N. A. Ratamess, "Hormonal responses and adaptations to resistance exercise and training," Sports Med, vol. 35, no. 4, pp. 339–361, 2005.

  6. T. M. Asikainen, S. Kukkonen-Harjula, and L. O. Miilunpalo, "Exercise for health for early postmenopausal women: a systematic review of randomised controlled trials," Sports Med, vol. 34, no. 11, pp. 753–778, 2004.

  7. K. Stokes, M. E. Nevill, and H. K. A. Lakomy, "The GH/IGF-I axis in exercise and sport," J. Appl. Physiol., vol. 92, no. 4, pp. 1560–1574, Apr. 2002.

This information has been medically reviewed by Dr Thom Phillips

Thom works in NHS general practice and has a decade of experience working in both male and female elite sport. He has a background in exercise physiology and has published research into fatigue biomarkers.

Dr Thom Philips, Head of Clinical Services, Forth

Dr Thom Phillips

Chief Medical Officer